ABSTRACT
Objective To explore the risk factors of malignant glaucoma of primary angle-closure glaucoma post operation.Methods The clinical data of 500 patients (705 eyes) with primary angle-closure glaucoma who received glaucoma surgery were retrospectivly analyzed.25 patients (30 eyes) with malignant glaucoma after surgery were selected as observation group,475 patients (675 eyes) with no malignant glaucoma after surgery were selected as the control group.The gender,age,type of glaucoma,preoperative intraocular pressure,anterior chamber depth,relative position of the lens , lens thickness , length of optic axis , corner structure and operation method of the two groups were recorded.Single factor analysis was conducted by chi-square test and t test,multiple factors analysis was conducted by Logistic regression analysis.Results Single factor analysis showed that there were significant differences in gender,age,glaucoma types,intraocular pressure and ocular axis length in the two groups (χ2 =5.394,4.785,6.475, 4.907,4.890,all P<0.05).Multivariable Logistic regression analysis results showed that age (OR=3.774,95%CI 1.765-3.774,P=0.004),and length of optic axis (OR=2.684,95% CI 1.363 to 6.953,P=0.005) were independent risk factors of primary angle -closure glaucoma post operation.Conclusion Women, younger age, chronic angle -closure glaucoma, continuous high intraocular pressure, corner completely closed, shallow anterior chamber,crystals thinner and shorter optic axis of primary angle -closure glaucoma patients prone to malignant glaucoma postoperation,especially younger age and optic axis short patients,should be given enough attention.